- Review Article
- Infection
- Pathogenetic and etiologic considerations of febrile seizures
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Ji Yoon Han, Seung Beom Han
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Clin Exp Pediatr. 2023;66(2):46-53. Published online January 13, 2023
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· Inflammatory responses accompanying fever increase neuronal excitability in the central nervous system, which in turn provokes seizures.
· Fever in children with febrile seizures is usually caused by common respiratory viruses, the distributions of which match those of seasonal community-acquired respiratory tract infections.
· Several genetic variations in ion channels seem associated with neuronal hyperexcitability in children with febrile seizures. |
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- Case Report
- Rheumatology
- Recurrent macrophage activation syndrome since toddler age in an adolescent boy with HLA B27 positive juvenile ankylosing spondylitis
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Joon Hyeong Park, Yu Mi Seo, Seung Beom Han, Ki Hwan Kim, Jung Woo Rhim, Nack Gyun Chung, Myung Shin Kim, Jin Han Kang, Dae Chul Jeong
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Clin Exp Pediatr. 2016;59(10):421-424. Published online October 17, 2016
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Recurrent macrophage activation syndrome (MAS) is very rare. We present the case of an adolescent boy with human leukocyte antigen (HLA) B27-positive ankylosing spondylitis (AS), who experienced episodes of recurrent MAS since he was a toddler. A 16-year-old boy was admitted because of remittent fever with pancytopenia and splenomegaly after surgical intervention for an intractable perianal abscess. He had been... |
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- Use of intravenous immunoglobulin in a disseminated varicella infection in an immunocompromised child
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Jae Hong Kim, Dae Hyun Kwon, E Young Bae, Seung Beom Han, Jae Wook Lee, Nack Gyun Chung, Dae Chul Jeong, Bin Cho, Jin Han Kang, Hack Ki Kim
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Clin Exp Pediatr. 2014;57(8):370-373. Published online August 25, 2014
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Varicella-zoster virus infection can lead to severe illness in immunocompromised patients. Further the mortality rate of disseminated varicella infection is extremely high particularly in immunocompromised children. We report a case of disseminated varicella infection in a child with acute lymphoblastic leukemia who was receiving chemotherapy, but was initially admitted with only for acute abdominal pain. The patient rapidly developed severe... |
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- Review Article
- BK virus-associated hemorrhagic cystitis after pediatric stem cell transplantation
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Seung Beom Han, Bin Cho, Jin Han Kang
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Clin Exp Pediatr. 2014;57(12):514-519. Published online December 31, 2014
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Hemorrhagic cystitis is a common stem cell transplantation-related complication. The incidence of early-onset hemorrhagic cystitis, which is related to the pretransplant conditioning regimen, has decreased with the concomitant use of mesna and hyperhydration. However, late-onset hemorrhagic cystitis, which is usually caused by the BK virus, continues to develop. Although the BK virus is the most common pathogenic microorganism of poststem... |
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- Original Article
- Regional differences in phylogenetic group of Escherichia coli strains isolated from children with urinary tract infection in Korea
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Ui-Yoon Choi, Seung Beom Han, Soo Young Lee, Jin Han Kang, Sun Mi Kim, Sang Hyuk Ma
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Clin Exp Pediatr. 2012;55(11):420-423. Published online November 23, 2012
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Purpose We phylogenetically analyzed the Escherichia coli strains isolated from children with urinary tract infection (UTI) in 2 regions of Korea. Virulence factors (VFs) and antibiotic resistance of the strains were also determined to compare the possible differences. MethodsA total of 138 E. coli strains were collected from the 2 regions; Gyeongin (78 strains) and Gyeongnam (60 strains). The phylogenetic groups were... |
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- Case Report
- A case of Kikuchi-Fujimoto disease with autoimmune thyroiditis
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Eun Ji Go, You Jin Jung, Seung Beom Han, Byung Kyu Suh, Jin Han Kang
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Clin Exp Pediatr. 2012;55(11):445-448. Published online November 23, 2012
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Kikuchi-Fujimoto disease (KFD) is a benign self-limiting disease characterized by fever and lymphadenitis. The etiology and pathogenesis of KFD is unclear. However, two hypotheses have been suggested: a viral infection hypothesis and an autoimmune hypothesis. Several KFD patients with various types of autoimmune diseases have been reported, and these reports support the hypothesis for autoimmune pathogenesis of KFD. Here, we... |
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